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(E)-3-Hydroxy-5-methoxystilbene

(E)-3-Hydroxy-5-methoxystilbene

Catalog No. BCN5292
Size Price Stock
20mg $298 In stock
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Quality Control of (E)-3-Hydroxy-5-methoxystilbene

Chemical structure

(E)-3-Hydroxy-5-methoxystilbene

Biological Activity of (E)-3-Hydroxy-5-methoxystilbene

1. (E)-3-Hydroxy-5-methoxystilbene possesses inhibitory activity against several Gram-positive bacteria, including isolates of methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium bovis BCG, and avirulent Bacillusanthracis (Sterne strain), among others.

(E)-3-Hydroxy-5-methoxystilbene Dilution Calculator

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(E)-3-Hydroxy-5-methoxystilbene Molarity Calculator

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Chemical Properties of (E)-3-Hydroxy-5-methoxystilbene

Cas No. 35302-70-6 SDF Download SDF
Chemical Name 3-methoxy-5-(2-phenylethenyl)phenol 3-methoxy-5-[(E)-2-phenylethenyl]phenol
SMILES COc1cc(O)cc(C=Cc2ccccc2)c1
Standard InChIKey JVIXPWIEOVZVJC-BQYQJAHWSA-N
Standard InChI InChI=1S/C15H14O2/c1-17-15-10-13(9-14(16)11-15)8-7-12-5-3-2-4-6-12/h2-11,16H,1H3/b8-7+
Type of Compound Phenols Appearance Powder
Formula C15H14O2 M.Wt 226.3
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of (E)-3-Hydroxy-5-methoxystilbene

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4189 mL 22.0946 mL 44.1891 mL 88.3783 mL 110.4728 mL
5 mM 0.8838 mL 4.4189 mL 8.8378 mL 17.6757 mL 22.0946 mL
10 mM 0.4419 mL 2.2095 mL 4.4189 mL 8.8378 mL 11.0473 mL
50 mM 0.0884 mL 0.4419 mL 0.8838 mL 1.7676 mL 2.2095 mL
100 mM 0.0442 mL 0.2209 mL 0.4419 mL 0.8838 mL 1.1047 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Preparation of (E)-3-Hydroxy-5-methoxystilbene

This product is isolated and purified from the herbs of Jatropha curcas

References on (E)-3-Hydroxy-5-methoxystilbene

New classes of Gram-positive selective antibacterials: inhibitors of MRSA and surrogates of the causative agents of anthrax and tuberculosis.[Pubmed: 18849164]


An antimicrobial phenolic stilbene, (E)-3-Hydroxy-5-methoxystilbene, 1 was recently isolated from the leaves of Comptonia peregrina (L.) Coulter and shown to possess inhibitory activity against several Gram-positive bacteria, including isolates of methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium bovis BCG, and avirulent Bacillusanthracis (Sterne strain), among others. These results prompted the design and synthesis of two new classes of compounds, phenoxystyrenes and phenothiostyrenes, as analogs of the natural antimicrobial stilbene. These and additional stilbenoid analogs were synthesized using new, efficient, copper-mediated coupling strategies. Minimum inhibitory concentration (MIC) antimicrobial assays were performed on all compounds prepared. These preliminary structure-activity relationship studies indicated that both new classes of synthetic analogs, as well as the stilbenes, show promising activity against Gram-positive bacteria when at least one phenolic moiety is present, but not when absent. The potencies of the phenolic phenoxystyrenes and phenothiostyrenes were found to be comparable to those of the phenolic stilbenes tested.

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