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(-)-[3R,4S]-Chromanol 293B

(-)-[3R,4S]-Chromanol 293B

Catalog No. BCC7080
Size Price Stock
10mg $208.00 Ship Within 7 Days
50mg $875.00 Ship Within 7 Days
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Quality Control of (-)-[3R,4S]-Chromanol 293B

Chemical structure

(-)-[3R,4S]-Chromanol 293B

Biological Activity of (-)-[3R,4S]-Chromanol 293B

Enantiomer that selectively inhibits the slow component of delayed rectifier K+ current (IKs). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC50 values are 1.36 and 9.6 μM respectively). Has negligible inhibitory action at KV11.1 (hERG) channels (IC50 > 30 μM). Racemate Chromanol 293B also available.

(-)-[3R,4S]-Chromanol 293B Dilution Calculator

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(-)-[3R,4S]-Chromanol 293B Molarity Calculator

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Chemical Properties of (-)-[3R,4S]-Chromanol 293B

Cas No. 163163-24-4 SDF Download SDF
Chemical Name N-[(3R,4S)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide
Formula C15H20N2O4S M.Wt 324.39
Solubility Soluble to 100 mM in ethanol with gentle warming and to 100 mM in DMSO with gentle warming
Storage Store at RT
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of (-)-[3R,4S]-Chromanol 293B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0827 mL 15.4135 mL 30.8271 mL 61.6542 mL 77.0677 mL
5 mM 0.6165 mL 3.0827 mL 6.1654 mL 12.3308 mL 15.4135 mL
10 mM 0.3083 mL 1.5414 mL 3.0827 mL 6.1654 mL 7.7068 mL
50 mM 0.0617 mL 0.3083 mL 0.6165 mL 1.2331 mL 1.5414 mL
100 mM 0.0308 mL 0.1541 mL 0.3083 mL 0.6165 mL 0.7707 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Kewords:

(-)-[3R,4S]-Chromanol 293B,163163-24-4,Membrane Transporter/Ion Channel,Potassium Channel, supplier, inhibitor,Antagonist,Blocker,Modulator,Agonist, activators, activates, potent, BioCrick

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